Genome editing reduces cholesterol in large animal model, laying human trial groundwork

Genome editing reduces cholesterol in large animal model, laying human trial groundwork


Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania. This is the first demonstration of a clinically relevant reduction of gene expression in a large animal model using genome editing.



from Biotech News